Found 14 matching trials
An Exploratory Study of the Effects of a Single Dose of QAX576 (an Interleukin-13 Monoclonal Antibody) on Simulated Hayfever PHASE2 This study will investigate whether a single dose QAX576 (an interleukin-13...
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Novartis Investigator Site
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Evaluation of Safety and Efficacy of Specific Immunotherapy With Recombinant Major Allergens of Timothy Grass Pollen Adsorbed Onto Aluminium-hydroxide in Patients With IgE-mediated Allergic Rhinoconjunctivitis +/- Controlled Asthma PHASE3 Efficacy and Safety from a high-dosed subcutaneous recombinant preparation...
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Allergopharma GmbH & Co. KG
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Standardising Nasal Allergen Challenge in Adult With Hay Fever NA Hay fever affects 1 in 4 of the UK population and has significant effects o...
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Royal Brompton Hospital
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Effects of Imatinib in Subjects With Seasonal Allergic Rhinitis and Who Are Sensitive to Timothy Grass Pollen PHASE1 This study will assess the effects of Imatinib on allergic inflammation fol...
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Novartis Investigative site
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Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen NA The investigators propose the development of a range of nasal spray challen...
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Imperial Clinical Respiratory Research Unit (ICRRU), St Mary's Hospital
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Dose-Response-Study With a Recombinant Cocktail of Phleum (rPhleum) Allergens PHASE2 Dose-response trial with a cocktail of recombinant major allergens of Timot...
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Prof. Dr. med. Ludger Klimek
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Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction PHASE2 The primary objective of this study is to assess whether the combination of...
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Royal Brompton Hospital
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Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis PHASE3 To investigate the immunologic effects and safety of 60-day treatment of th...
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Research facility ID ORG-001086
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The Effects of OC000459 on Nasal Mediators PHASE1 This is the first proof of concept study for OC000459 and is undertaken to ...
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National Heart & Lung Institute Clinical Studies Unit
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Repeat Nasal Allergen Challenge PHASE2 This is a non-drug, biomarker study to assess the utility of the model of r...
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National Heart & Lung Institute Clinical Studies Unit
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